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Bladder calculi

  • Bladder calculi are uncommon in the Western world
  • They are well described in ancient medical literature
  • Hippocrates wrote about the management of bladder stone
  • Operations to remove stones via the perineum were described in the centuries BC
  • Suprapubic lithotomy was described in the 15th century
  • Transurethral lithotomy became popular in the 18th century
  • Lithotripsy was first described in 1822
  • Surgery was often associated with significant morbidity and mortality

Pathophysiology

  • Bladder calculi are usually associated with urinary stasis
  • Urinary infections increase the risk of stone formation
  • Foreign bodies (e.g. suture material) can also act as a nidus for stone formation
  • They can however form in a normal bladder
  • There is no recognised association with ureteric calculi
  • Most bladder calculi form in the bladder and are not from the upper urinary tract
  • They vary in size and can be multiple
  • They are more common in elderly men
  • In Asia, they are seen more commonly in children
  • Most stones in adults are formed of uric acid
  • Long-standing untreated bladder stones are associated with squamous cell carcinoma

Clinical features

  • Bladder calculi can be asymptomatic
  • Common symptoms include
    • Suprapubic pain
    • Dysuria
    • Haematuria
  • Abdominal examination may be normal

Diagnosis

  • Historically stones were diagnosed by the passage of urethral 'sounds'
  • Today thy can be identified on
    • Plain abdominal x-ray
    • Bladder ultrasound
    • CT scan
    • Cystoscopy
  • Uric acid stones are radiolucent but may have an opaque calcified layer
  • Patients may present in acute urinary retention

Plain abdominal x-ray showing a bladder calculus

Picture provided by Sandip Sinha, King George University Hospital, Ludinow, India

Surgery

  • Indications for surgery include
    • Recurrent urinary tract infections
    • Acute urinary retention
    • Frank haematuria
  • Any underlying bladder abnormality should be sought
  • Historically the surgical approach involved 'cutting for a stone'
  • This was via either a perineal or suprapubic approach
  • The three common approaches today are
    • Transurethral cystolitholapaxy
    • Percutaneous cystolitholapaxy
    • Open suprapubic cystostomy
  • Extracorporeal shockwave lithotripsy is relatively ineffective
  • Complications of cystolitholapaxy include
    • Infection
    • Haemorrhage
    • Bladder perforation
    • Hyponatraemia

Open suprapubic cystotomy

Picture provided by Sandip Sinha, King George University Hospital, Ludinow, India

Bibliography

Schwartz B F,  Stoller M L.  The vesical calculus.  Urol Clin North Am 2000;  27:  333-346.

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