MEN 1 Syndrome (Wermer's Syndrome)
| Hyperparathyroidism |
90% |
| Pancreatic Islet Cell Tumours |
60% |
| Gastrinoma |
60% |
| Insulinoma |
10% |
| Vipoma |
|
| PPoma |
|
| Glucagonoma |
|
| Pituitary Tumours |
5% |
| Prolactinoma |
|
| GH, ACTH, TSH secreting tumours |
|
| Thyroid adenoma |
|
| Adrenal adenoma |
|
| Carcinoid tumours |
|
MEN 2a Syndrome (Sipple's Syndrome)
| Medullary Thyroid Carcinoma |
100% |
| Phaeochromocytoma |
50% |
| Hyperparathyroidism |
10% |
MEN 2b Syndrome
| Medullary Thyroid Carcinoma |
100% |
| Phaeochromocytoma |
50% |
| Multiple mucosal neuromas |
100% |
| Ganglioneuromatosis of the gut |
100% |
| Marfanoid appearance |
100%> |
Bibliography
Aldridge M C. Islet cell tumours: surgical management. Hosp Med 2000; 61:
830-833.
Learoyd D L, Delbridge L W, Robinson B G. Multiple endocrine neoplasia. Aust NZ J
Med 2000; 30: 75-82.
Mullen M H, Gauger P G, Thompson N W. Endocrine tumours of the pancreas: review and recent
advances. Aust NZ J Surg 2001; 71: 754-482.
Play J E, Moley J F, Lairmore T C. Multiple endocrine neoplasias. Semin Surg Oncol
2000; 18: 328-332.
Proye C A, Nguyen H H. Current perspective in the surgery for multiple endocrine neoplasias. Aust
NZ J Surg 1999; 69: 106-116.
Taheri S, Meeran K. Islet cell tumours. diagnosis and medical management. Hosp Med 2000;
61: 824-829. |