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Benign breast disease

Breast anatomy

Classification of benign breast disease

Normal Benign disorder Benign disease
Development Duct development Nipple inversion Mammary fistula
Lobular development Fibroadenoma Giant fibroadenoma
Stromal development Hypertrophy
Cyclical change Hormonal activity Mastalgia
Epithelial activity Duct papilloma
Pregnancy Epithelial hyperplasia Blood-stained discharge
Lactation Galactocele
Involution Duct involution Duct ectasia Periductal mastitis
Cysts Nipple retraction Ductal hyperplasia
Epithelial hyperplasia Micropapillomatosis Lobular hyperplasia
Sclerosing adenosis

Relationship between benign and malignant breast disease

No increased risk

  • Sclerosing adenosis
  • Apocrine change
  • Duct ectasia
  • Mild hyperplasia
  • Fibroadenoma
  • Cysts
  • Apocrine metaplasia

Slight increased risk (1.5 to 2 times)

  • Moderate or florid hyperplasia
  • Papilloma with fibro vascular core

Moderate increased risk (4 to 5 times)

  • Atypical ductal hyperplasia
  • Atypical lobular hyperplasia

High risk (8 to 10 times)

  • Ductal carcinoma in-situ
  • Lobular carcinoma in-situ

Galactocele

Picture provided by Adisa Adeyinka, University Teaching Hospital, Aba, NIgeria

Bibliography

Hamed H,  Fentiman I S.  Benign breast disease. Int J Clin Pract 2001;  55:  464-464.

Marchant D J.   Benign breast disease.  Obstet Clin North Am 2002;  29:  1-20.

Santen R J,  Mansel R.  Benign breast disorders.  N Engl J Med 2005;  353:  275-285

 

 
 

Last updated: 05 January 2008

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