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Respiratory physiology

Respiratory anatomy

  • The thoracic cage is formed by
    • 12 thoracic vertebrae
    • 12 ribs - the top 10 attach directly or indirectly to the sternum
    • Sternum
    • Diaphragm muscle
  • Within the thoracic cage are 3 compartments
    • The 2 pleural cavities, each with a lung
    • The mediastinum, containing the heart
  • Gases enter and leave lungs through
    • Mouth and nose
    • Pharynx and larynx
    • Trachea
    • Bronchi
    • Bronchioles
  • These tubes expand at their ends into alveoli, where gas exchange takes place
  • There are about 23 branchings which lead to about 300 million alveoli

Respiratory mechanics

  • Contracting the diaphragm or raising the ribs expands the thoracic cavity
  • At rest contraction of the diaphragm accounts for most of inspiration
  • The diaphragm is supplied by phrenic nerve which originates from cervical spinal cord (C3-C5)
  • The external intercostal muscles also aid inspiration
  • At rest expiration is mostly passive and lungs contract due to elasticity
  • During exercise the internal intercostal muscles and others aid expiration
  • Pull ribs downward and inward, reducing thoracic cavity

Pulmonary ventilation

  • The total amount of air moved in and out of the lungs each minute depends upon two factors
    • Tidal volume
    • Respiratory rate
  • Pulmonary ventilation = RR x TV
  • During exercise both RR and TV can be increased
  • The extra inspiration available is called the inspiratory reserve volume (IRV)
  • The extra expiration available is called the expiratory reserve volume (ERV)
  • After maximum expiration some air is still present in the lungs and is know as the residual volume (RV)
  • The maximum volume available for breathing is the vital capacity (VC)
  • Vital capacity = IRV + TV = ERV

Author:  Dr Shakeeb Khan

 

 
 

Last updated: 05 January 2008

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